The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 02, 2008

Filed:

Oct. 14, 2004
Applicants:

Han-qing Dong, Syosset, NY (US);

Kenneth Foreman, Syosset, NY (US);

Mark Joseph Mulvihill, East Northport, NY (US);

Anthony Innocenzo Nigro, Westwood, NJ (US);

Arno G. Steinig, East Northport, NY (US);

Douglas Werner, Holtsville, NY (US);

Robin Wilkes, Oxfordshire, GB;

Inventors:

Han-Qing Dong, Syosset, NY (US);

Kenneth Foreman, Syosset, NY (US);

Mark Joseph Mulvihill, East Northport, NY (US);

Anthony Innocenzo Nigro, Westwood, NJ (US);

Arno G. Steinig, East Northport, NY (US);

Douglas Werner, Holtsville, NY (US);

Robin Wilkes, Oxfordshire, GB;

Assignee:

OSI Pharmaceuticals, Inc., Melville, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/00 (2006.01); C07D 471/00 (2006.01); C07D 487/00 (2006.01); C07D 491/00 (2006.01); C07D 495/00 (2006.01); C07D 497/00 (2006.01); C07D 415/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds of the formula and pharmaceutically acceptable salts thereof, wherein Qand Rare defined herein, inhibit the IGF-1R enzyme and are useful for the treatment and/or prevention of various diseases and conditions that respond to treatment by inhibition of tyrosine kinases.


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