The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 02, 2008
Filed:
Mar. 26, 2003
Akira Kaneko, Niigata, JP;
Akira Kaneko, Niigata, JP;
Asubio Pharma Co., Ltd., Tokyo, JP;
Abstract
The present invention provides a method for preparing a β-lactam compound of the following Formula (3), which comprises the step of reacting a compound of the following Formula (1) with a trialkyl phosphite represented by the formula (RO)P (wherein Rrepresents an ethyl group, etc.) in an amount of 2 to 5 moles per mole of the compound and the step of heating the resulting reaction mixture in a diluent, wherein said method is characterized by having the step of completely removing unreacted trialkyl phosphite from the reaction mixture prior to the step of heating. (wherein X represents S, etc., Y represents N, etc., n represents 0 or 1, Rrepresents an optionally substituted alkyl group containing 1 to 10 carbon atoms, etc., Rand Reach represent an optionally substituted alkyl or heterocyclic group, etc., and Rrepresents an alkenyloxy group containing 1 to 6 carbon atoms, etc., provided that Rand Rmay together form a β-lactam ring, etc.)