The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 02, 2008
Filed:
Jul. 03, 2004
Kumar Sahoo Prabhat, Chennai, IN;
Anandam Vempali, Chennai, IN;
Sivakumaran Sundaravadivelan, Chennai, IN;
Nagesh Ganesh Praveen, Chennai, IN;
Manikrao Waghdare Vittal, Chennai, IN;
Balawant Deshpande Pandurang, Chennai, IN;
Kumar Luthra Parven, Chennai, IN;
Ramesh Sathe Pratik, Chennai, IN;
Kumar Sahoo Prabhat, Chennai, IN;
Anandam Vempali, Chennai, IN;
Sivakumaran Sundaravadivelan, Chennai, IN;
Nagesh Ganesh Praveen, Chennai, IN;
Manikrao Waghdare Vittal, Chennai, IN;
Balawant Deshpande Pandurang, Chennai, IN;
Kumar Luthra Parven, Chennai, IN;
Ramesh Sathe Pratik, Chennai, IN;
Orchid Chemicals & Pharmaceuticals Ltd., Chennai, IN;
Abstract
The present invention relates to an improved process for the preparation of Cefditoren of formula (I), the said process comprising the steps of: i) converting the compound of formula (II) to a compound of the formula (III) using TPP and sodium iodide in the presence of THF, water, and base; ii) reacting the compound of formula (III) with 4-methyl-5-formyl-thiazole to produce a compound of formula (IV); iii) deesterifying the compound of the formula (IV) to yield compound of formula (V); iv) converting the compound of formula (V) to compound of formula (VI) in the presence of a base and solvent; v) converting the compound of formula (VI) into compound of formula (VII) by enzymatic hydrolysis; and vi) reacting compound of formula (VII) with compound of formula (VIII) in the presence of solvent and base to produce compound of formula (I).
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile