The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 02, 2008
Filed:
Mar. 19, 2007
Masakazu Fujio, Tokyo, JP;
Hiroyuki Satoh, Tokyo, JP;
Shinya Inoue, Tokyo, JP;
Toshifumi Matsumoto, Tokyo, JP;
Yasuhiro Egi, Tokyo, JP;
Masakazu Fujio, Tokyo, JP;
Hiroyuki Satoh, Tokyo, JP;
Shinya Inoue, Tokyo, JP;
Toshifumi Matsumoto, Tokyo, JP;
Yasuhiro Egi, Tokyo, JP;
Mitsubishi Tanabe Pharma Corporation, Osaka, JP;
Abstract
The present invention relates to an isoquinoline compound represented by the following formula (I), an optically active form thereof, a pharmaceutically acceptable salt thereof, a water adduct thereof, a hydrate thereof and a solvate thereof, as well as an agent for the prophylaxis and/or treatment of a disease caused by hyperreactivity of poly(ADP-ribose)polymerase, containing the compound, and a poly(ADP-ribose)polymerase inhibitor containing the compound. In addition, this compound is useful as an agent for the prophylaxis and/or treatment of cerebral infarction, particularly as an agent for the prophylaxis and/or treatment of acute cerebral infarction. Furthermore, this compound is useful as a prophylactic and/or therapeutic agent that improves neurological symptoms associated with cerebral infarction, particularly acute cerebral infarction. wherein the symbols are the same as defined in the description.