The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 25, 2008
Filed:
Nov. 02, 2005
Applicant:
Dennis J. Kalota, Fenton, MO (US);
Inventor:
Dennis J. Kalota, Fenton, MO (US);
Assignee:
Mallinckrodt Inc., Hazelwood, MO (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 209/08 (2006.01); C07C 211/17 (2006.01); C07C 211/27 (2006.01);
U.S. Cl.
CPC ...
Abstract
This present invention relates to a process for preparing benzylated amines by the reaction of an amine selected from methamphetamine and propylhexedrine with benzyl halide. Numerous improvements are obtained by employing the amine in molar excess with respect to benzyl halide, preferably in a molar ratio of 2 to 1. The excess amine is employed to selectively neutralize by-product acid as the amine salt. The amine salt is then separated from the reaction mixture and basified to reclaim starting amine for recycle to the process.