The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 25, 2008
Filed:
Apr. 28, 2005
Walter Ferdinand Maria Filliers, Vremde, BE;
Rudy Laurent Maria Broeckx, Turnhout, BE;
Patrick René Angibaud, Fontaine-Bellenger, FR;
Walter Ferdinand Maria Filliers, Vremde, BE;
Rudy Laurent Maria Broeckx, Turnhout, BE;
Patrick René Angibaud, Fontaine-Bellenger, FR;
Janssen Pharmaceutica N.V., Beerse, BE;
Abstract
A diastereoselective synthesis process for the preparation of an enantiomer of 6-[amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone which comprises the conversion of (±)-6-[chloro(4-chlomphenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone into a compound of formula (VIII) wherein aryl is phenyl substituted once or twice with Calkyloxy or naphtalenyl substituted once or twice with Calkyloxy.