The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 25, 2008
Filed:
May. 21, 2004
Tibor Keler, Ottsville, PA (US);
Israel Lowy, Dobbs Ferry, NY (US);
Laura A. Vitale, Doylestown, PA (US);
Diann Blanset, Hillsborough, NJ (US);
Mohan Srinivasan, Cupertino, CA (US);
Tibor Keler, Ottsville, PA (US);
Israel Lowy, Dobbs Ferry, NY (US);
Laura A. Vitale, Doylestown, PA (US);
Diann Blanset, Hillsborough, NJ (US);
Mohan Srinivasan, Cupertino, CA (US);
Medarex, Inc., Princeton, NJ (US);
Abstract
Isolated human monoclonal antibodies which bind to Anthrax protective antigen are disclosed. The human antibodies can be produced in a non-human transgenic animal, e.g., a transgenic mouse, capable of producing multiple isotypes of human monoclonal antibodies by undergoing V-D-J recombination and isotype switching. Also disclosed are derivatives of the human antibodies (e.g., bispecific antibodies and immunoconjugates), pharmaceutical compositions comprising the human antibodies, non-human transgenic animals and hybridomas which produce the human antibodies, and therapeutic and diagnostic methods for using the human antibodies.