The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 25, 2008
Filed:
May. 21, 2004
Kevin G. Pinney, Woodway, TX (US);
Phyllis Arthasary, Waco, TX (US);
Anupama Shirali, Hamden, CT (US);
Klaus Edvardsen, Lund, SE;
David J. Chaplin, Watlington, GB;
Kevin G. Pinney, Woodway, TX (US);
Phyllis Arthasary, Waco, TX (US);
Anupama Shirali, Hamden, CT (US);
Klaus Edvardsen, Lund, SE;
David J. Chaplin, Watlington, GB;
Baylor University, Waco, TX (US);
OXiGENE, Inc., Waltham, MA (US);
Abstract
Chrome compounds have been discovered which demonstrate impressive cytotoxicity as well as a remarkable ability to inhibit tubulin polymerization. Such compounds as well as related derivatives are excellent clinical candidates for the treatment of cancer in humans. In addition, certain of these ligands, as pro-drugs, may well prove to be tumor selective vascular targeting chemotherapeutic agents or to have vascular targeting activity resulting in the selective prevention and/or destruction of nonmalignant proliferating vasculature.