The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 25, 2008
Filed:
Apr. 29, 2003
James Aggen, San Francisco, CA (US);
John H. Griffin, Atherton, CA (US);
Mathai Mammen, San Mateo, CA (US);
Daniel Marquess, Half Moon Bay, CA (US);
Edmund J. Moran, San Francisco, CA (US);
David Oare, Belmont, CA (US);
James Aggen, San Francisco, CA (US);
John H. Griffin, Atherton, CA (US);
Mathai Mammen, San Mateo, CA (US);
Daniel Marquess, Half Moon Bay, CA (US);
Edmund J. Moran, San Francisco, CA (US);
David Oare, Belmont, CA (US);
Theravance, Inc., South San Francisco, CA (US);
Abstract
Disclosed are multibinding compounds which are muscarinic receptor antagonists. The multibinding compounds of this invention containing from 2 to 10 ligands covalently attached to one or more linkers. Each ligand is, independently of each other, a muscarinic receptor antagonist or an allosteric modulator provided that at least one of said ligand is a muscarinic receptor antagonist. The multibinding compounds of this invention are useful in the treatment and prevention of diseases such as chronic obstructive pulmonary disease, chronic bronchitis, irritable bowel syndrome, urinary incontinence, and the like.