The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 25, 2008

Filed:

Jul. 01, 2004
Applicants:

Alexandru T. Balaban, Galveston, TX (US);

William A. Seitz, Dickinson, TX (US);

Marc A. C. Ilies, Philadelphia, PA (US);

Edward Bradbridge Thompson, Galveston, TX (US);

Robert E. Garfield, Galveston, TX (US);

Betty H. Johnson, Beaumont, TX (US);

Aaron L. Miller, Galveston, TX (US);

Melissa J. Wentz, Pearland, TX (US);

Inventors:

Alexandru T. Balaban, Galveston, TX (US);

William A. Seitz, Dickinson, TX (US);

Marc A. C. Ilies, Philadelphia, PA (US);

Edward Bradbridge Thompson, Galveston, TX (US);

Robert E. Garfield, Galveston, TX (US);

Betty H. Johnson, Beaumont, TX (US);

Aaron L. Miller, Galveston, TX (US);

Melissa J. Wentz, Pearland, TX (US);

Assignee:

The Texas A&M University System, College Station, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/02 (2006.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
Abstract

Pyridinium cationic lipids useful as non-viral gene delivery agents are disclosed. The agents are prepared by reaction of pyrylium salts with primary amines. Also disclosed are methods of trasfectind cells using the pyridinium cationic lipids as gene transfer agents.


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