The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 25, 2008

Filed:

Oct. 30, 2002
Applicants:

Thierry Imbert, Viviers les Montagnes, FR;

Barbara Monse, Weichs, DE;

Wouter Koek, San Antonio, CA (US);

Inventors:

Thierry Imbert, Viviers les Montagnes, FR;

Barbara Monse, Weichs, DE;

Wouter Koek, San Antonio, CA (US);

Assignee:

Pierre Fabre Medicament, Boulogne Billancourt, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4353 (2006.01); A61K 31/4365 (2006.01); A61K 31/46 (2006.01); C07D 471/04 (2006.01); C07D 419/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention concerns compounds of general formula 1, wherein: A, B, D and E represent one or two nitrogen atoms, the others being carbon atoms; X represents a S or, a O, thereby forming a bicyclic fused heteroaromatic, such as thieno[2,3-b]pyridine, furo[2,3-b]pyridine, thieno[3,2-b]pyridine, furo[3,2-b]pyridine, thieno[2,3-b]pyrazine, furo[2,3-b]pyrazine, thieno[2,3-c]pyridine, furo[2,3-c]pyridine, thieno[3,2-c]pyridine and furo[3,2-c]pyridine; R1 represents a linear or branched C-Calkoxy group, a linear or branched C-Calkylthio group; R2 represents a linear, branched, cyclic C-Cgroup, a 2- or 3-thienylmethyl group, or a benzyl group optionally substituted by one or several halogens, F, Cl, Br, I, C-Calkyl, C-Calkoxy, CF3, CN, NO2, OH; and their pharmaceutically acceptable salts. Said compounds are anti-dopaminergic agents.


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