The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 25, 2008
Filed:
Apr. 08, 2002
Daniel Chu, Santa Clara, CA (US);
Rustum Boyce, San Francisco, CA (US);
David Duhl, Oakland, CA (US);
Bryan Chang, Concord, CA (US);
Daniel Chu, Santa Clara, CA (US);
Rustum Boyce, San Francisco, CA (US);
David Duhl, Oakland, CA (US);
Bryan Chang, Concord, CA (US);
Novartis Vaccines and Diagnostics, Inc., Emeryville, CA (US);
Abstract
Compounds having the general structure I are provided. X and Y are independently selected from the group consisting of CH, N, NR, C═O, C═S, S═O, SO, S, O, (CRR), C(═O)—(CRR), and C(═S)—(CRR), where n is 1, 2, or 3. W is selected from the group consisting of (formula I) and L is selected from the group consisting of N, O, S═O, SO, C(O), NC(O), NC(S), OC(O), OC(S), C(NR), C(NOR), and a covalent bond. Z, Z, and Zare independently selected from the group consisting of substituted carbon and nitrogen. Compounds of formula I are agonists of the melanocortin-4 receptor ('MC-4r2) and therefore may have useful properties for controlling diseases related to MC-4r action in humans, such as obesity and type II diabetes.