The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 25, 2008

Filed:

Aug. 27, 2001
Applicants:

Xianxhang Yu, Mauldin, SC (US);

Thomas E. Wagner, Greer, SC (US);

Inventors:

Xianxhang Yu, Mauldin, SC (US);

Thomas E. Wagner, Greer, SC (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/16 (2006.01); A61K 38/33 (2006.01); A61K 45/00 (2006.01); C07K 14/195 (2006.01); C07K 14/435 (2006.01);
U.S. Cl.
CPC ...
Abstract

A cytotoxin can be rendered non-toxic by charge neutralizing the amino acids salient to pore assembly and/or sterically inhibiting formation of the peptide's active conformation. In the presence of specific proteases, the inactive peptide or procytotoxin can be activated to assemble into its lytic conformation and selectively destroy a target cell.


Find Patent Forward Citations

Yu, Xianxhang. (2008). Lytic peptide prodrugs (U.S. Patent No. 7456146). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7456146

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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