The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 25, 2008
Filed:
Dec. 02, 2003
Frida Ryttsén, Göteborg, SE;
Owe Orwar, Hovås, SE;
Mikael Levin, Hisings Backa, SE;
Eskil Sahlin, Göteborg, SE;
Joakim Wigström, Västra Frolunda, SE;
Frida Ryttsén, Göteborg, SE;
Owe Orwar, Hovås, SE;
Mikael Levin, Hisings Backa, SE;
Eskil Sahlin, Göteborg, SE;
Joakim Wigström, Västra Frolunda, SE;
Cellectricon AB, Gothenburg, SE;
Abstract
The invention provides hollow-tip-electrodes for spatially localized delivery of substances to one or more biological targets present in a population comprising target and non-target molecules, macromolecules, and/or cells. The invention also provides electrode plates for receiving one or more of such tips, tip-electrode plates comprising electrode plates comprising one or more electrode tips, and systems comprising tip-electrodes and containers for containing one or more biological targets, e.g., such as molecules, macromolecules, and/or cells. The invention further provides methods for using such systems and components thereof. In one preferred aspect, the systems are used for spatially confined electroporation of cells and cell structures. The invention facilitates high throughput screening of agents (e.g., such as drugs) that act on intracellular targets.