The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 25, 2008
Filed:
Jan. 12, 2006
Xiaowen Liu, Cupertino, CA (US);
Kirsten Essenmacher, Palo Alto, CA (US);
David A. Simpson, Redwood City, CA (US);
Qiang Xu, Cupertino, CA (US);
Xiaowen Liu, Cupertino, CA (US);
Kirsten Essenmacher, Palo Alto, CA (US);
David A. Simpson, Redwood City, CA (US);
Qiang Xu, Cupertino, CA (US);
Osel, Inc., Santa Clara, CA (US);
Abstract
This disclosure relates to a modified version of cyanovirin-N protein and a transformedbacterium that is capable of recombinantly expressing this modified protein. Further disclosed are polynucleotide sequence encoding the modified cyanovirin-N protein, expression cassette that allows the expression of the modified protein, and method of make and use of the modified protein as well as the transformedbacterium. In addition, this disclosure describes two novel promoters originated from, which are capable of directing a high level of gene expression inbacteria. Also described are an expression cassette comprising one of the novel promoters, a genetically modifiedbacterium containing the expression cassette, a method for recombinant gene expression inbacteria using the novel promoters, and a method for delivery of proteins with desired biological activity to a mucosal surface in a human.