The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 18, 2008

Filed:

Dec. 31, 2003
Applicants:

Timothy Kirk Gallaher, San Gabriel, CA (US);

Lena A. Bealle, Tujanga, CA (US);

Kai-jin Wu, Los Angeles, CA (US);

Yi Zhao, South Pasadena, CA (US);

Unnati Jarlwata, Anaheim, CA (US);

Inventors:

Timothy Kirk Gallaher, San Gabriel, CA (US);

Lena A. Bealle, Tujanga, CA (US);

Kai-Jin Wu, Los Angeles, CA (US);

Yi Zhao, South Pasadena, CA (US);

Unnati Jarlwata, Anaheim, CA (US);

Assignee:

University of Southern California, Los Angeles, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/435 (2006.01); C07K 14/475 (2006.01); C12P 21/02 (2006.01); A61K 38/18 (2006.01);
U.S. Cl.
CPC ...
Abstract

A novel mammalian protein system is disclosed. This system comprises a secreted protein factor and its related membrane-bound splice variant. These novel proteins have no homology to any known protein or class or protein, yet are ubiquitously expressed in nearly all tissue types. Also disclosed are novel nucleic acids that encode the novel polypeptides of the invention. The protein system was discovered in purified populations of murine hematopoieitc stem cells. The cDNAs of the invention were cloned from a marine hematopoietic lineage negative (Lin) library.


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