The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 18, 2008
Filed:
Jun. 10, 2004
Wolfgang Glaesner, Indianapolis, IN (US);
Rohn Lee Millican, Jr., Indianapolis, IN (US);
Andrew Mark Vick, Fishers, IN (US);
Wolfgang Glaesner, Indianapolis, IN (US);
Rohn Lee Millican, Jr., Indianapolis, IN (US);
Andrew Mark Vick, Fishers, IN (US);
Eli Lilly and Company, Indianapolis, IN (US);
Abstract
The invention provides specific GLP-1 analogs fused to specific IgG4-Fc derivatives. These fusion proteins have an increased half-life, decreased immunogenicity, and reduce effector activity. The fusion proteins are useful in treating diabetes, obesity, irritable bowel syndrome and other conditions that would be benefited by lowering plasma glucose, inhibiting gastric and/or intestinal motility and inhibiting gastric and/or intestinal emptying, or inhibiting food intake.