The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 18, 2008

Filed:

Mar. 29, 2007
Applicants:

Alistair Lochead, Charenton le Pont, FR;

Mourad Saady, Paris, FR;

Franck Slowinski, Thieux, FR;

Philippe Yaiche, Les Lias, FR;

Inventors:

Alistair Lochead, Charenton le Pont, FR;

Mourad Saady, Paris, FR;

Franck Slowinski, Thieux, FR;

Philippe Yaiche, Les Lias, FR;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/506 (2006.01); A61K 31/444 (2006.01); A61P 3/10 (2006.01); A61P 25/28 (2006.01); C07D 401/14 (2006.01); C07D 403/14 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to therapeutic uses of a 2-(diaza-bicyclo-alkyl)-pyrimidone derivative represented by formula (I): Wherein R1, R2, R3, R4 and n are as defined herein. Specifically, the compounds of formula (I) are used for preventive and/or therapeutic treatment of a neurodegenerative disease caused by abnormal activity of GSK3β, such as Alzheimer's disease. The invention relates also to intermediates for the preparation of compound of formula (I).


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