The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 18, 2008
Filed:
Jul. 26, 2004
Andrew V. Schally, Miami, FL (US);
Jozsef Varga, Metairie, LA (US);
Marta Zarandi, Szeged, HU;
Ren Zhi Cai, New Orleans, LA (US);
Andrew V. Schally, Miami, FL (US);
Jozsef Varga, Metairie, LA (US);
Marta Zarandi, Szeged, HU;
Ren Zhi Cai, New Orleans, LA (US);
The Administrare's of the Tulane Educational Fund, New Orleans, LA (US);
United States of America by Dept of Veterans Affairs, Washington, DC (US);
Abstract
There is provided a novel series of synthetic antagonistic analogs of hGH-RH(1-29)NH. These analogs inhibit the activity of endogenous hGH-RH on the pituitary GH-RH receptors, and therefore prevent the release of growth hormone. The analogs also inhibit the proliferation of human cancers through a direct effect on the cancer cells. The higher inhibitory potencies of the new analogs, as compared to previously described ones, results from replacement of various amino acids.