The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 18, 2008

Filed:

Jan. 28, 2004
Applicants:

Mona Ståhle-bäckdahl, Stockholm, SE;

Johan Heilborn, Stockholm, SE;

Anders Carlsson, Stockholm, SE;

Conny Bogentoft, Hässelby, SE;

Inventors:

Mona Ståhle-Bäckdahl, Stockholm, SE;

Johan Heilborn, Stockholm, SE;

Anders Carlsson, Stockholm, SE;

Conny Bogentoft, Hässelby, SE;

Assignee:

Lipopeptide AB, Stockholm, SE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/17 (2006.01); A61K 47/44 (2006.01); A61P 17/02 (2006.01); C07K 14/47 (2006.01); C12N 5/08 (2006.01);
U.S. Cl.
CPC ...
Abstract

Use of the antimicrobial cathelicidin peptide ll-37, N-terminal fragments of LL-37 or extended sequences of LL-37 having 1-3 amino acids in the C-terminal end, for stimulating proliferation of epithalial and stromal cells and thereby healing of wounds, such as chronic ulcers. The cytotoxic effect of LL-37 may be reduced by including a bilayer-forming polar lipid, especially a digalactosyldiacylglycerol, in pharmaceutical compositions and growth media comprising LL-37.


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