The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 18, 2008
Filed:
Aug. 02, 2004
Pierre Deslongchamps, Sherbrooke, CA;
Yves Dory, Cookshire, CA;
Mark Peterson, Rock Forest, CA;
Kamel Benakli, Montreal, CA;
Eric Marsault, Sherbrooke, CA;
Luc Ouellet, Sherbrooke, CA;
Mahesh Ramaseshan, Sunnyvale, CA (US);
Martin Vézina, Rock Forest, CA;
Daniel Fortin, Montreal, CA;
Ruoxi Lan, Arlington, MA (US);
Shigui LI, Arlington, MA (US);
Gérald Villeneuve, Montreal, CA;
Hamid Hoveyda, Sherbrooke, CA;
Sylvie Beaubien, Sherbrooke, CA;
Graeme L Fraser, Sherbrooke, CA;
Pierre Deslongchamps, Sherbrooke, CA;
Yves Dory, Cookshire, CA;
Mark Peterson, Rock Forest, CA;
Kamel Benakli, Montreal, CA;
Eric Marsault, Sherbrooke, CA;
Luc Ouellet, Sherbrooke, CA;
Mahesh Ramaseshan, Sunnyvale, CA (US);
Martin Vézina, Rock Forest, CA;
Daniel Fortin, Montreal, CA;
Ruoxi Lan, Arlington, MA (US);
Shigui Li, Arlington, MA (US);
Gérald Villeneuve, Montreal, CA;
Hamid Hoveyda, Sherbrooke, CA;
Sylvie Beaubien, Sherbrooke, CA;
Graeme L Fraser, Sherbrooke, CA;
Tranzyme Pharma, Inc., , CA;
Abstract
Novel spatially-defined macrocyclic compounds containing specific conformational control elements are disclosed. Libraries of these macrocycles are then used to select one or more macrocycle species that exhibit a specific interaction with a particular biological target. In particular, compounds according to the invention are disclosed as agonists or antagonists of a mammalian motilin receptor and a mammalian ghrelin receptor.