The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 18, 2008
Filed:
Mar. 21, 2005
Joseph D. Gold, San Francisco, CA (US);
Mohammad Hassanipour, Danville, CA (US);
Lila R. Collins, Fremont, CA (US);
Chunhui Xu, Palo Alto, CA (US);
Joseph D. Gold, San Francisco, CA (US);
Mohammad Hassanipour, Danville, CA (US);
Lila R. Collins, Fremont, CA (US);
Chunhui Xu, Palo Alto, CA (US);
Geron Corporation, Menlo Park, CA (US);
Abstract
This invention provides a new procedure for generating cardiomyocyte lineage cells from embryonic stem cells for use in regenerative medicine. Differentiating by way of embryoid body formation or in serum is no longer required. Instead, the stem cells are plated onto a solid substrate, and differentiated in the presence of select factors and morphogens. After enrichment for cells with the appropriate phenotype, the cells are allowed to cluster into cardiac bodies™, which are remarkably homogeneous and suitable for the treatment of heart disease.