The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 11, 2008

Filed:

Oct. 08, 2004
Applicants:

Qiang Ding, San Diego, CA (US);

Yongping Xie, San Diego, CA (US);

Nathanael S. Gray, San Diego, CA (US);

Shuli You, San Diego, CA (US);

Greg Chopiuk, San Diego, CA (US);

Jiqing Jiang, San Diego, CA (US);

Yi Liu, San Diego, CA (US);

Ruo Steensma, La Jolla, CA (US);

Xing Wang, San Diego, CA (US);

Taebo Sim, San Diego, CA (US);

Inventors:

Qiang Ding, San Diego, CA (US);

Yongping Xie, San Diego, CA (US);

Nathanael S. Gray, San Diego, CA (US);

Shuli You, San Diego, CA (US);

Greg Chopiuk, San Diego, CA (US);

Jiqing Jiang, San Diego, CA (US);

Yi Liu, San Diego, CA (US);

Ruo Steensma, La Jolla, CA (US);

Xing Wang, San Diego, CA (US);

Taebo Sim, San Diego, CA (US);

Assignee:

IRM LLC, Hamilton, BM;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 215/38 (2006.01); C07D 471/02 (2006.01); C07D 251/38 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of the Abl, BCR-Abl, CSK, JNK1, JNK2, PDGF-R, p38, p70S6K, TGFβ, SRC, EGFR, c-Kit, trkB, FGFR3, Fes, Lck, Syk, RAF, MKK4, MKK6 and SAPK2β kinases.


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