The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 11, 2008
Filed:
Feb. 24, 2003
Steve S. Sommer, Duarte, CA (US);
Jinong Feng, Arcadia, CA (US);
Carolyn Buzin, Arcadia, CA (US);
Jin Yan, Duarte, CA (US);
Jeffrey Towbin, Houston, TX (US);
Steve S. Sommer, Duarte, CA (US);
Jinong Feng, Arcadia, CA (US);
Carolyn Buzin, Arcadia, CA (US);
Jin Yan, Duarte, CA (US);
Jeffrey Towbin, Houston, TX (US);
City of Hope, Duarte, CA (US);
Baylor College of Medicine, Houston, TX (US);
Abstract
The present invention relates generally to the field of human genetics. Specifically, the present invention relates to methods and materials used to detect a human sporadic DCM predisposing gene, specifically the dystrophin gene, some mutant alleles of which cause susceptibility to sporadic DCM. More specifically, the invention relates to germline mutations in the dystrophin gene and their use in the diagnosis of predisposition to sporadic DCM. The invention also relates to the prophylaxis and/or therapy of sporadic DCM associated with a mutation in the dystrophin gene. The invention further relates to the screening of drugs for sporadic DCM therapy. Finally, the invention relates to the screening of the dystrophin gene for mutations/alterations, which are useful for diagnosing the predisposition to sporadic DCM.