The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 11, 2008

Filed:

Apr. 21, 2005
Applicants:

Todd Andrew Brugel, West Chester, OH (US);

Jennifer Anne Townes, Loveland, OH (US);

Michael Philip Clark, Maineville, OH (US);

Mark Sabat, Loveland, OH (US);

Adam Golebiowski, Loveland, OH (US);

Biswanath DE, Cincinnati, OH (US);

Stephen Matthew Berberich, Alexandria, OH (US);

Gregory Kent Bosch, West Chester, OH (US);

Inventors:

Todd Andrew Brugel, West Chester, OH (US);

Jennifer Anne Townes, Loveland, OH (US);

Michael Philip Clark, Maineville, OH (US);

Mark Sabat, Loveland, OH (US);

Adam Golebiowski, Loveland, OH (US);

Biswanath De, Cincinnati, OH (US);

Stephen Matthew Berberich, Alexandria, OH (US);

Gregory Kent Bosch, West Chester, OH (US);

Assignee:

The Procter & Gamble Company, Cincinnati, OH (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 239/48 (2006.01); A61K 31/506 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to 1,1,3-tri-substituted ureas which inhibit the extracellular release of inflammatory cytokines, said cytokines responsible for one or more human or higher mammalian disease states. The present invention further relates to compositions comprising said 1,1,3-tri-substituted ureas which inhibit the extracellular release of inflammatory cytokines, and methods for preventing, abating, or otherwise controlling enzymes which are understood to be the active components responsible for the herein described disease states.


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