The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 04, 2008
Filed:
Jul. 01, 2003
Reddy Bandi Parthasaradhi, Hyderabad, IN;
Reddy Kura Rathnakar, Hyderabad, IN;
Reddy Rapolu Raji, Hyderabad, IN;
Reddy Dasari Muralidhara, Hyderabad, IN;
Reddy Bandi Parthasaradhi, Hyderabad, IN;
Reddy Kura Rathnakar, Hyderabad, IN;
Reddy Rapolu Raji, Hyderabad, IN;
Reddy Dasari Muralidhara, Hyderabad, IN;
Hetero Drugs Limited, Hyderabad, Andrapradesh, IN;
Abstract
A simple, industrial process for the preparation of the intermediates of acetyl cholinesterase inhibitors is provided. Thus, for example, 5,6-dimethoxy-2-(4-pyridyl)methyl-1-indanone is hydrogenated using platinum oxide catalyst in the presence of hydrochloric acid under a pressure of 2 bars to give 4-[(5,6-dimethoxy-1-indanon)-2-yl]methylpiperidine hydrochloride, which is then converted to donepezil hydrochloride, an acetyl cholinesterase inhibitor.