The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 04, 2008
Filed:
Mar. 16, 2004
Blake Pepinsky, Arlington, MA (US);
Laura Runkel, Cambridge, MA (US);
Margot Brickelmaier, Boxford, MA (US);
Adrian Whitty, Hopkinton, MA (US);
Paula Hochman, Newton, MA (US);
Blake Pepinsky, Arlington, MA (US);
Laura Runkel, Cambridge, MA (US);
Margot Brickelmaier, Boxford, MA (US);
Adrian Whitty, Hopkinton, MA (US);
Paula Hochman, Newton, MA (US);
Biogen Idec MA Inc., Cambridge, MA (US);
Abstract
An interferon beta polypeptide comprising interferon-beta 1a coupled to a polymer containing a polyalkylene glycol moiety wherein the interferon-beta-1a and the polyalkylene glycol moiety are arranged such that the interferon-beta-1a has an enhanced activity relative to another therapeutic form of interferon beta (interferon-beta-1b) and exhibits no decrease in activity as compared to non-conjugated interferon-beta-1a. The conjugates of the invention are usefully employed in therapeutic as well as non-therapeutic, e.g., diagnostic, applications.