The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 04, 2008
Filed:
Apr. 12, 2005
Applicants:
Jianxin Gu, River Edge, NJ (US);
Ping Cai, New City, NY (US);
Mark E. Ruppen, Garnerville, NY (US);
Inventors:
Assignee:
Wyeth, Madison, NJ (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12P 17/16 (2006.01); C12P 17/18 (2006.01);
U.S. Cl.
CPC ...
Abstract
Methods for the synthesis of regiospecific rapamycin 42-hemiesters and regiospecific FK506 32-esters with dicarboxylic acids is described. The methods involve catalyzing the reaction between a rapamycin or a FK-506 and a dicarboxylic anhydride or a bifunctional activated ester of dicarboxylic acid with a lipase.