The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 04, 2008
Filed:
Mar. 19, 2003
Masato Ikeda, Nagano, JP;
Mikiro Hayashi, Machida, JP;
Junko Ohnishi, Nagano, JP;
Satoshi Mitsuhashi, Hofu, JP;
Hiroshi Mizoguchi, Machida, JP;
Satoshi Nakagawa, Machida, JP;
Masato Ikeda, Nagano, JP;
Mikiro Hayashi, Machida, JP;
Junko Ohnishi, Nagano, JP;
Satoshi Mitsuhashi, Hofu, JP;
Hiroshi Mizoguchi, Machida, JP;
Satoshi Nakagawa, Machida, JP;
Kyowa Hakko Kogyo Co., Ltd., Tokyo, JP;
Abstract
The present invention provides a polypeptide comprising an amino acid sequence in which at least one amino acid is deleted, substituted or added in an amino acid sequence of isopropylmalate isomerase derived from a microorganism belonging to coryneform bacteria, wherein a coryneform bacterium which produces the polypeptide comprising the amino acid sequence as the sole isopropylmalate isomerase exhibits a partial leucine requirement in a minimal medium; a DNA encoding the polypeptide, a recombinant DNA comprising the DNA, a microorganism transformed with the recombinant DNA, and a process for producing an L-amino acid using the microorganism.