The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 04, 2008
Filed:
Jan. 26, 2005
Rodney J. Y. Ho, Seattle, WA (US);
Ziping Yang, Shoreline, WA (US);
Danny D. Shen, Edmonds, WA (US);
Daniel Wu, Bellevue, WA (US);
Rodney J. Y. Ho, Seattle, WA (US);
Ziping Yang, Shoreline, WA (US);
Danny D. Shen, Edmonds, WA (US);
Daniel Wu, Bellevue, WA (US);
University of Washington, Seattle, WA (US);
Abstract
Provided are compositions relating to novel MDR1 polymorphisms, including nucleic acids, polypeptides, and recombinant cells, as well as methods for detection of MDR1 polymorphisms in biological samples and elucidation of the influence of MDR1 polymorphisms on MDR1 protein function. Also provided are a rat MRP1 cDNA and protein, stable cell lines expressing the rat MRP1 protein, and methods of assessing drug penetration or disposition in a cell line expressing a recombinant mammalian MRP1 or MDR1 protein, or a homolog thereof.