The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 04, 2008

Filed:

Aug. 19, 2002
Applicant:

Deepak K. Thassu, West Henrietta, NY (US);

Inventor:

Deepak K. Thassu, West Henrietta, NY (US);

Assignee:

L. Perrigo Company, Allegan, MI (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/14 (2006.01); A61K 9/48 (2006.01); A61K 9/64 (2006.01); A61K 9/20 (2006.01); A61K 9/16 (2006.01);
U.S. Cl.
CPC ...
Abstract

A method of obtaining improved reproducibility of dissolution profiles of dosage forms containing pharmaceutically active particles includes steps of screening raw pharmaceutically active particles to obtain or isolate particles having a desired monomodal particle size distribution. The particles having a monomodal particle size distribution may be incorporated into a solid oral dosage form to provide a highly reproducible dissolution profile. Two or more collections or particles having different monomodal particle size distributions may be combined and incorporated into solid oral dosage forms to provide predictable dissolution profiles.


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