The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 04, 2008
Filed:
Sep. 09, 2003
Hideo Niwa, Akashi, JP;
Takeshi Fukuchi, Kobe, JP;
Ichiro Shimizu, Osaka, JP;
Masao Sato, Kobe, JP;
Akiko Nishi, Akashi, JP;
Kenji Yamashita, Takamatsu, JP;
Tadashi Kaneko, Tokorozawa, JP;
Hajime Ohgushi, Kashihara, JP;
Koji Hattori, Kashihara, JP;
Kota Uematsu, Kashihara, JP;
Hideo Niwa, Akashi, JP;
Takeshi Fukuchi, Kobe, JP;
Ichiro Shimizu, Osaka, JP;
Masao Sato, Kobe, JP;
Akiko Nishi, Akashi, JP;
Kenji Yamashita, Takamatsu, JP;
Tadashi Kaneko, Tokorozawa, JP;
Hajime Ohgushi, Kashihara, JP;
Koji Hattori, Kashihara, JP;
Kota Uematsu, Kashihara, JP;
Kaneka Corporation, Osaka, JP;
GC Corporation, Tokyo, JP;
Natl. Inst. of Adv. Ind. Science & Tech., Tokyo, JP;
Abstract
The present invention provides a scaffold in which cells can be stably retained and grafted in a uniform distribution state in the culture, preferable proliferation ability and viability can be secured, and particularly in the case of cartilage, fixation treatment such as suture can be carried out in the transplantation into affected parts after the culture, and the mechanical strength is provided sustainable for (weighted) compression at the initial stage of transplantation. The present invention relates to a 3-dimensional porous scaffold for tissue regeneration Further, the invention relates to the above 3-dimensional porous scaffold in which seeding properties of cells are improved by a pore enlargement treatment of one side face by a separation operation, a salt elution operation of a surface part, or a combination of these operations. It becomes possible to produce a 3-dimensional cell combination having excellent degree of tissue formation and medical treatment effect by seeding a cell or precursor cell derived from a tissue in this scaffold, and culturing them in an artificial environment and/or the living body.