The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 28, 2008
Filed:
May. 11, 2007
Min GE, Edison, NJ (US);
Jiafang He, Dayton, NJ (US);
Fiona Wai Yu Lau, Edgewater, NJ (US);
Gui-bai Liang, Scotch Plains, NJ (US);
Songnian Lin, Monroe, NJ (US);
Weiguo Liu, Princeton, NJ (US);
Shawn P. Walsh, Bridgewater, NJ (US);
Lihu Yang, Edison, NJ (US);
Min Ge, Edison, NJ (US);
Jiafang He, Dayton, NJ (US);
Fiona Wai Yu Lau, Edgewater, NJ (US);
Gui-Bai Liang, Scotch Plains, NJ (US);
Songnian Lin, Monroe, NJ (US);
Weiguo Liu, Princeton, NJ (US);
Shawn P. Walsh, Bridgewater, NJ (US);
Lihu Yang, Edison, NJ (US);
Merck & Co., Inc., Rahway, NJ (US);
Abstract
Tricyclic compounds containing a cyclopropyl carboxylic acid or carboxylic acid derivative (e.g. amide) fused to a bicyclic ring, including pharmaceutically acceptable salts and prodrugs thereof, are agonists of G-protein coupled receptor 40 (GPR40) and are useful as therapeutic compounds, particularly in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia.