The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 28, 2008
Filed:
Jul. 13, 2004
John L. Buchanan, Brookline, MA (US);
Daniel Elbaum, Newton, MA (US);
Matthew W. Martin, Cambridge, MA (US);
David C. Mcgowan, Arlington, MA (US);
Perry M. Novak, Milford, MA (US);
Joseph J. Nunes, Andover, MA (US);
John L. Buchanan, Brookline, MA (US);
Daniel Elbaum, Newton, MA (US);
Matthew W. Martin, Cambridge, MA (US);
David C. McGowan, Arlington, MA (US);
Perry M. Novak, Milford, MA (US);
Joseph J. Nunes, Andover, MA (US);
Amgen Inc., Thousand Oaks, CA (US);
Abstract
The present invention relates to pyrimidine or pyridine carbamate compounds having the general Formula I: and pharmaceutically acceptable salts or derivatives thereof. Also included are methods of treatment of various diseases and conditions, including inflammation, inhibition of T cell activation and proliferation, arthritis, organ transplant, ischemic or reperfusion injury, myocardial infarction, stroke, multiple sclerosis, inflammatory bowel disease, Crohn's disease, lupus, hypersensitivity, type 1 diabetes, psoriasis, dermatitis, Hashimoto's thyroiditis, Sjogren's syndrome, autoimmune hyperthyroidism, Addison's disease, autoimmune diseases, glomerulonephritis, allergic diseases, asthma, hayfever, eczema, cancer, colon carcinoma, thymoma, just to name a few, in a mammal, the methods comprising administering a therapeutically-effective amount a compound of Formula I, or a salt or derivative form thereof, as described above.