The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 28, 2008

Filed:

Sep. 02, 2005
Applicants:

Chieko Kitaura, Osaka, JP;

Kenjiro Minomi, Osaka, JP;

Katsuyuki Okubo, Osaka, JP;

Keisaku Okada, Osaka, JP;

Natsuko Kagehisa, Osaka, JP;

Masashi Kamiyama, Osaka, JP;

Zheng Hou, Vista, CA (US);

Jian Liu, San Diego, CA (US);

Yucheng Song, Oceanside, CA (US);

Lei Yu, Carlsbad, CA (US);

Inventors:

Chieko Kitaura, Osaka, JP;

Kenjiro Minomi, Osaka, JP;

Katsuyuki Okubo, Osaka, JP;

Keisaku Okada, Osaka, JP;

Natsuko Kagehisa, Osaka, JP;

Masashi Kamiyama, Osaka, JP;

Zheng Hou, Vista, CA (US);

Jian Liu, San Diego, CA (US);

Yucheng Song, Oceanside, CA (US);

Lei Yu, Carlsbad, CA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61K 9/06 (2006.01); A61K 38/22 (2006.01); A61K 38/28 (2006.01); A61K 47/42 (2006.01); C07K 14/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compositions and methods are disclosed for the treatment of diabetes and related diseases using peptides with incretin hormone activity. Preferably, the peptide with incretin hormone activity is GLP-1, exendin or an analog of GLP-1 or exendin. The peptides with incretin hormone activity are administered transepithelially using a transepithelial carrier peptide. The transepithelial peptide contains sufficient amino, guanidine or amidino groups to stimulate transepithelial delivery. In some embodiments, the transepithelial carrier and the peptide with incretin hormone activity are embedded in a pressure sensitive adhesive layer of a plaster or patch.


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