The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 28, 2008
Filed:
Sep. 01, 2000
Francois Mallet, Villeurbanne, FR;
Francois-loic Cosset, Lyons, FR;
Jean-luc Blond, Lyons, FR;
Dimitri Lavillette, Bercenay le Hay, FR;
Olivier Bouton, Francheville, FR;
Alessia Ruggieri, Mulhouse, FR;
Francois Mallet, Villeurbanne, FR;
Francois-Loic Cosset, Lyons, FR;
Jean-Luc Blond, Lyons, FR;
Dimitri Lavillette, Bercenay le Hay, FR;
Olivier Bouton, Francheville, FR;
Alessia Ruggieri, Mulhouse, FR;
Biomerieux, Marcy l'Etoile, FR;
Institut National de la Sante et de la Recherche Medicale, Paris, FR;
Abstract
A method for detecting the expression of a polypeptide in cells and for detecting the interaction between a polypeptide and cells, ex vivo or in vitro, wherein the polypeptide is selected from the group consisting of: a peptide comprising the cyt domain of the envelope protein of the human endogenous retrovirus, HERV-W; a peptide comprising amino acids 448-538 of SEQ ID NO: 1; and a peptide comprising a sequence having, for any series of 20 amino acids, at least 80% identity with amino acids 448-538 of SEQ ID NO: 1. Detection is established by the fusogenic power of the polypeptide, which is demonstrated by syncytia formation.