The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 28, 2008
Filed:
Jun. 20, 2003
Laurent Cavarec, Paris, FR;
Ilya Chumakov, Vaux-le-Penil, FR;
Benoit Destenaves, Brunoy, FR;
Catherine Gonthier, Corbeil-Essonnes, FR;
Isabelle Elias, Sonchamp, FR;
Laurent Cavarec, Paris, FR;
Ilya Chumakov, Vaux-le-Penil, FR;
Benoit Destenaves, Brunoy, FR;
Catherine Gonthier, Corbeil-Essonnes, FR;
Isabelle Elias, Sonchamp, FR;
Serono Genetics Institute, S.A., Evry, FR;
Abstract
The invention encompasses polypeptides and polynucleotides of three novel bipolar disorder-associated potassium channel polypeptides, KCNQ2-15bx, KCNQ2-15by and KCNQ2-15bz. The invention further relates to the use of potassium channels comprising KCNQ2 subunits for screening for modulators thereof, the use of these modulators for treating mental disorders such as bipolar disorder, schizophrenia and depression, and drugs comprising these modulators. The invention also discloses biallelic markers located in the KCNQ2 gene and their use for diagnosing mental disorders.