The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 28, 2008

Filed:

Aug. 06, 2004
Applicants:

David Piwnica-worms, Laduc, MO (US);

Kathryn Luker, Ann Arbor, MI (US);

Gary Luker, Ann Arbor, MI (US);

Inventors:

David Piwnica-Worms, Laduc, MO (US);

Kathryn Luker, Ann Arbor, MI (US);

Gary Luker, Ann Arbor, MI (US);

Assignee:

Washington University, St. Louis, MO (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/66 (2006.01); G01N 33/53 (2006.01); C12N 15/62 (2006.01);
U.S. Cl.
CPC ...
Abstract

An enhanced firefly luciferase protein fragment complementation assay method is described that produces a robust and broadly applicable bioluminescence signal and demonstrates both modification-independent and phosphorylation-dependent protein interactions in intact living human cells and animals useful as a diagnostic and testing tool in living biologic systems in research and in assays.


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