The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 28, 2008
Filed:
Sep. 16, 2002
Jennifer M. Burns, San Mateo, CA (US);
Zhenhua Miao, San Jose, CA (US);
Zheng Wei, Redwood City, CA (US);
Maureen C. Howard, Los Altos, CA (US);
Brett A. Premack, San Carlos, CA (US);
Thomas J. Schall, Palo Alto, CA (US);
Jennifer M. Burns, San Mateo, CA (US);
Zhenhua Miao, San Jose, CA (US);
Zheng Wei, Redwood City, CA (US);
Maureen C. Howard, Los Altos, CA (US);
Brett A. Premack, San Carlos, CA (US);
Thomas J. Schall, Palo Alto, CA (US);
ChemoCentryx, Inc., Mountain View, CA (US);
Abstract
The present invention provides methods for identifying an agent that specifically binds and/or modulates one topology of chemokine receptor but not a second topology of the receptor. Such agents are useful as therapeutics for diseases or conditions associated with a particular chemokine receptor topology. Moreover, the agents are useful for detecting a particular topology of a chemokine receptor, thereby diagnosing disease or predisposition for a disease. In addition, the agents are useful for identifying and isolating cells that express a particular topology of a chemokine receptor.