The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 28, 2008
Filed:
Aug. 21, 2003
Irving Boime, St. Louis, MO (US);
David Ben-menahem, St. Louis, MO (US);
Irving Boime, St. Louis, MO (US);
David Ben-Menahem, St. Louis, MO (US);
Washington University, St. Louis, MO (US);
Abstract
Forms of differentially acting glycoprotein hormones are disclosed. These compositions are of the formulaβ-(linker)-α-(linker)-β;  (1)β-(linker)-β-(linker)-α;  (2)α-(linker)-β-(linker)-β;  (3)β≈α-(linker)-β; or  (4)β-(linker)-α≈β  (5) wherein each of βand βhas the amino acid sequence of the β subunit of a vertebrate glycoprotein hormone or a variant of said amino acid sequence, as variants are defined herein. 'α' designates the α subunit of a vertebrate glycoprotein hormone or a variant thereof, 'linker' refers to a covalently linked moiety that spaces the βand βsubunits at appropriate distances from the α subunit and from each other. “≈” is a noncovalent link. Each of m and n is independently 0 or 1.