The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 21, 2008
Filed:
Apr. 08, 2004
Susan R. Webb, Leucadia, CA (US);
Ola Winqvist, Uppsala, SE;
Lars Karlsson, La Jolla, CA (US);
Michael R. Jackson, Del Mar, CA (US);
Per A. Peterson, Rancho Santa Fe, CA (US);
Susan R. Webb, Leucadia, CA (US);
Ola Winqvist, Uppsala, SE;
Lars Karlsson, La Jolla, CA (US);
Michael R. Jackson, Del Mar, CA (US);
Per A. Peterson, Rancho Santa Fe, CA (US);
The Scripps Research Institute, La Jolla, CA (US);
Abstract
The present invention relates to synthetic antigen-presenting matrices, their methods of making and their methods of use. One such matrix is cells that have been transfected to produce MHC antigen-presenting molecules with one or more accessory molecules. The matrices are used to activate naive CD4T cells as well as shift the ongoing activation state into a preferred differentiated population of either Th1 or Th2 cells.