The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 21, 2008

Filed:

Mar. 01, 2001
Applicants:

Johan Stenflo, Malmö, SE;

Loisa Mary Stenberg, Malmö, SE;

Mark Alan Brown, Malmö, SE;

Inventors:

Johan Stenflo, Malmö, SE;

Loisa Mary Stenberg, Malmö, SE;

Mark Alan Brown, Malmö, SE;

Assignee:

Protease AB, Malmo, SE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/18 (2006.01); C07K 1/22 (2006.01); G01N 33/543 (2006.01); G01N 33/573 (2006.01); G01N 33/577 (2006.01);
U.S. Cl.
CPC ...
Abstract

Antibodies are described, which are suitable for identification of γ-carboxyglutamic acid (Gla), said antibodies having an ability of identifying Gla residues in proteins and/or peptides, while not reacting with glutamic (Glu) residues in corresponding proteins and/or peptides. Methods for the preparation and identification of said antibodies as well as methods for detection of Gla in biological fluids, tissue extracts, tissue specimens, in which methods said antibodies are used, are also described. There is also described the use of said antibodies for immunopurification of Gla-containing proteins or peptides by, for instance, immunoprecipitation or immunoaffinity chromatography.


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