The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 21, 2008

Filed:

Oct. 07, 2003
Applicants:

Samuel Achilefu, St. Louis, MO (US);

Raghavan Rajagopalan, Solon, OH (US);

Richard B. Dorshow, St. Louis, MO (US);

Joseph E. Bugaj, St. Charles, MO (US);

Muthunadar P. Periasamy, Chesterfield, MO (US);

Inventors:

Samuel Achilefu, St. Louis, MO (US);

Raghavan Rajagopalan, Solon, OH (US);

Richard B. Dorshow, St. Louis, MO (US);

Joseph E. Bugaj, St. Charles, MO (US);

Muthunadar P. Periasamy, Chesterfield, MO (US);

Assignee:

Mallinckrodt, Inc., St. Louis, MO (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 10/00 (2006.01); A61B 5/00 (2006.01); A61B 8/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Highly hydrophilic indole and benzoindole derivatives that absorb and fluoresce in the visible region of light are disclosed. These compounds are useful for physiological and organ function monitoring. Particularly, the molecules of the invention are useful for optical diagnosis of renal and cardiac diseases and for estimation of blood volume in vivo.


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