The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 14, 2008
Filed:
May. 14, 2003
Jaekyoon Shin, Keumkok-Dong, Kwanson-Ku, Suwon-Si, Kyonggi-Do, KR;
Han-woong Lee, Seongnam, KR;
Goo Taeg OH, Daejeon, KR;
Jaekyoon Shin, Keumkok-Dong, Kwanson-Ku, Suwon-Si, Kyonggi-Do, KR;
Han-Woong Lee, Seongnam, KR;
Goo Taeg Oh, Daejeon, KR;
Other;
Samsung Electronics, Co., Ltd., Suwon-si, Gyeonggi-do, KR;
Abstract
The application discloses a role of p62 in aging-related disease, such as development of obesity, type 2 diabetes mellitus, non-alcoholic fatty liver, various tumors, increased male mortality, intracellular inclusion named sequestosome, and redox regulation. In particular the application discloses a method of detecting the formation of inclusion bodies in neurodegenerative diseases. The invention further relates to a method of screening for therapeutic agents that disperse the inclusions. Further, transgenic mice containing a mutation in the p62 gene and having a functionally disrupted p62 gene locus are also disclosed.