The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 14, 2008
Filed:
Apr. 09, 2003
Applicants:
Mladen Mercep, Zagreb, HR;
Milan Mesic, Zagreb, HR;
Dijana Pesic, Sibenik, HR;
Ivana Ozimec, Trnovec, HR;
Inventors:
Mladen Mercep, Zagreb, HR;
Milan Mesic, Zagreb, HR;
Dijana Pesic, Sibenik, HR;
Ivana Ozimec, Trnovec, HR;
Assignee:
GlaxoSmithKline Istrazivacki Center Zagreb D.O.O., Zagreb, HR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/381 (2006.01); C07D 495/04 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention relates to compounds of 2-thia-dibenzoazulene class, to their pharmacologically acceptable salts and solvates, to processes and intermediates for the preparation thereof as well as to their antiinflammatory effects, especially to the inhibition of tumour necrosis factor-α(TNF-α) production and the inhibition of interleukin-1 (IL-1) production as well as to their analgetic action.