The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 14, 2008

Filed:

Sep. 01, 2005
Applicants:

Wei Chen, Fremont, CA (US);

Penglie Zhang, Foster City, CA (US);

James B. Aggen, Burlingame, CA (US);

Daniel Joseph Dairaghi, Palo Alto, CA (US);

Andrew M. K. Pennell, San Francisco, CA (US);

Subhabrata Sen, Bangalore Karnataka, IN;

J. J. Kim Wright, Redwood City, CA (US);

Inventors:

Wei Chen, Fremont, CA (US);

Penglie Zhang, Foster City, CA (US);

James B. Aggen, Burlingame, CA (US);

Daniel Joseph Dairaghi, Palo Alto, CA (US);

Andrew M. K. Pennell, San Francisco, CA (US);

Subhabrata Sen, Bangalore Karnataka, IN;

J. J. Kim Wright, Redwood City, CA (US);

Assignee:

ChemoCentryx, Inc., Mountain View, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds are provided that act as potent modulators of one or more of the CCR1, CCR2 and CCR3 receptors. The compounds are generally fused-, spiro- or bridged-nitrogen heterocycles having an aryl and heteroaryl component and are useful in pharmaceutical compositions, methods for the treatment of CCR1-, CCR2- and/or CCR3-mediated diseases, and as controls in assays for the identification of competitive receptor antagonists for the above chemokine receptors.


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