The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 07, 2008

Filed:

Aug. 14, 2006
Applicants:

Clark Pan, Castro Valley, CA (US);

Andreas M. Knorr, Erkrath, DE;

Michael Schauer, Wuppertal, DE;

Claudia Hirth-dietrich, Wuppertal, DE;

Sabine Kraft, Planegg, DE;

Barbara Krebs, Bergisch Gladbach, DE;

Inventors:

Clark Pan, Castro Valley, CA (US);

Andreas M. Knorr, Erkrath, DE;

Michael Schauer, Wuppertal, DE;

Claudia Hirth-Dietrich, Wuppertal, DE;

Sabine Kraft, Planegg, DE;

Barbara Krebs, Bergisch Gladbach, DE;

Assignee:

Bayer HealthCare LLC, Tarrytown, NY (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 21/00 (2006.01); C12N 5/10 (2006.01); C12N 15/00 (2006.01); C07H 21/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Human antibodies that bind to TIMP-1 can be used as reagents to diagnose and treat disorders in which TIMP-1 is elevated, such as liver fibrosis, alcoholic liver disease, cardiac fibrosis, acute coronary syndrome, lupus nephritis, glomerulosclerotic renal disease, benign prostate hypertrophy, colon cancer, lung cancer, and idiopathic pulmonary fibrosis.


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