The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 07, 2008

Filed:

Sep. 07, 2005
Applicants:

Takeshi Kitahara, Tokyo, JP;

Hidenori Watanabe, Nagareyama, JP;

Kunio Ando, Kawasaki, JP;

Inventors:

Takeshi Kitahara, Tokyo, JP;

Hidenori Watanabe, Nagareyama, JP;

Kunio Ando, Kawasaki, JP;

Assignee:

NRL Pharma, Inc., Kawasaki-shi, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/075 (2006.01); C07C 43/30 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention has an object to develop novel compounds which are effective for the therapy of syndrome X, cancer, myxedema, vascular chronic inflammation and the like, and furthermore prevent/treat the restenosis caused in an artery expansion by a balloon or a stent and have the activity facilitating regenerative medicine by inhibiting rejection of own cells or tissues to be transplanted and the method for preparing the same. Novel acetal derivatives obtained by acylating the hydroxyl group at the 2-position of the orcylaldehyde which ascochlorin and its analogs have and thereafter bonding an alcohol to the aldehyde group in the presence of a basic catalyst are found to achieve the object.


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