The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 07, 2008
Filed:
Jun. 15, 2007
Applicants:
Shaomeng Wang, Saline, MI (US);
Jiangyong Chen, Ann Arbor, MI (US);
Inventors:
Shaomeng Wang, Saline, MI (US);
Jiangyong Chen, Ann Arbor, MI (US);
Assignee:
The Regents of the University of Michigan, Ann Arbor, MI (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/225 (2006.01); A61K 31/11 (2006.01); A61K 31/70 (2006.01);
U.S. Cl.
CPC ...
Abstract
This invention relates to compositions comprising co-crystals of (−)-gossypol with a Ccarboxylic acid or Csulfonic acid which are useful as inhibitors of Bcl-2 family proteins. The invention also relates to the use of co-crystals of (−)-gossypol with a Ccarboxylic acid or Csulfonic acid for inducing apoptosis in cells and for sensitizing cells to the induction of apoptotic cell death.