The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 07, 2008
Filed:
Jul. 08, 2004
Jonas Boström, Mölndal, SE;
Kay Brickmann, Mölndal, SE;
Patrik Holm, Pargas, FI;
Pernilla Sandberg, Mölndal, SE;
Marianne Swanson, Mölndal, SE;
Christer Westerlund, Mölndal, SE;
Jonas Boström, Mölndal, SE;
Kay Brickmann, Mölndal, SE;
Patrik Holm, Pargas, FI;
Pernilla Sandberg, Mölndal, SE;
Marianne Swanson, Mölndal, SE;
Christer Westerlund, Mölndal, SE;
AstraZeneca AB, Sodertalje, SE;
Abstract
The present invention relates to certain novel compounds of the Formula I to processes for preparing such compounds, to their the utility in modulation of nuclear hormone receptors Liver X Receptor (LXR)α(NR1H3) and/or β(NR1H2) and in treating and/or preventing clinical conditions including cardiovascular diseases such as atherosclerosis; inflammatory diseases, Alzheimer's disease, lipid disorders (dyslipidemias) whether or not associated with insulin resistance, type 2 diabetes and other manifestations of the metabolic syndrome, to methods for their therapeutic use and to pharmaceutical compositions containing them.